I-Urolithin A, Yongeza amandla eSeluli yoLusu, ivuselele i-Collagen, kunye nokuchasana neempawu zokuguga

Urolithin A

Inkcazelo emfutshane:

I-Urolithin A yi-metabolite enamandla ye-postbiotic, eveliswa xa iibhaktheriya zamathumbu ziphula i-ellagitannins (efumaneka kwiirharnati, amajikijolo, kunye namantongomane). Kwi-skincare, ibhiyozelwa ukuba isebenzeimitophagy-inkqubo yeselula "yokucoca" esusa i-mitochondria eyonakele. Oku kwandisa ukuveliswa kwamandla, ukulwa noxinzelelo lwe-oxidative, kunye nokukhuthaza ukuhlaziywa kwezicubu. Ilungele ulusu oluqolileyo okanye oludiniweyo, luzisa iziphumo eziguqukayo zokuchasa ukuguga ngokubuyisela amandla esikhumba ngaphakathi.

Igama loRhwebo:I-Cosmate® UA

Igama lemveliso:Urolithin A

INCI Igama:Urolithin A

Inombolo yeCAS:1143 - 70 - 0

Imiyalezo ekwi-Intanethi I-imeyile WhatsApp

Iinkcukacha zeMveliso

Kutheni iZhonghe Fountain

Iithegi zeMveliso

Urolithin Ayi-metabolite eveliswa yi-gut bacteria esuka kwi-ellagitannins-eyenzeka ngokwemvelo i-polyphenols efumaneka kwiirharnati, amajikijolo kunye namantongomane. Isaziwa ngokusebenza kwayo okungaqhelekanga, esi sithako siye savela njengenkqubela phambili kwimixube yezithambiso, ibonelela ngenkqubo exhaswa yisayensi yokuvuselela ulusu.UrolithinA isebenza kwinqanaba leselula ukuxhasa impilo ye-mitochondrial, "izindlu zamandla" zeeseli zesikhumba, ezibaluleke kakhulu kwimveliso yamandla kunye nokulungiswa kwezicubu. Ngokulungisa umsebenzi we-mitochondrial, inceda ukuvuselela ukukhathala, ukuxinezeleka kwesikhumba, ukunciphisa ukubonakala kokukhathala kunye nokubuyisela ukukhanya okukhanyayo, ulutsha. Amandla ayo okuvuselela i-collagen kunye ne-elastin synthesis yomeleza ngakumbi ukwakheka kolusu, ukunciphisa imigca ecolekileyo, imibimbi, kunye nokuhexa.UrolithinI-A izinzile kwiindlela ezahlukeneyo, ukusuka kwiiserum ezikhaphukhaphu ukuya kwiikhrimu ezityebileyo. Idibanisa ngaphandle komthungo kunye nezinye izithako ezisebenzayo ezifana ne-hyaluronic acid, ivithamin C, kunye ne-retinol, iphucula ukusebenza kwayo ngelixa igcina ukuhambelana kolusu.

Umsebenzi oPhambili we-Urolithin A:

Yandisa umsebenzi we-mitochondrial kwiiseli zolusu ukunyusa imveliso yamandla

Ivuselela i-collagen kunye ne-elastin synthesis yokuphucula ukuqina kolusu

Yehlisa uxinzelelo lwe-oxidative kwaye yenza ii-radicals zasimahla zingasebenzi

Ixhasa umsebenzi wokuthintela ulusu kunye nokugcinwa kwe-hydration

Inciphisa iimpawu zokuguga (imigca emihle, imibimbi, ubuthuntu).

Indlela yokwenzaUrolithin A:

I-Urolithin A yenza iziphumo zayo ngeendlela ezininzi:

Inkxaso yeMitochondrial: Ivuselela i-mitophagy-inkqubo yendalo apho iiseli zisusa i-mitochondria eyonakalisiweyo kwaye ithathe indawo yayo entsha, esebenzayo. Le nkqubo yokuhlaziya iphucula imveliso yamandla eselula, iphucula ukukwazi kwesikhumba ukulungisa nokuhlaziya

Ukhuselo lwe-Antioxidant: Njenge-antioxidant enamandla, ikhupha ii-radicals zasimahla ezenziwe kukuvezwa kwe-UV kunye noxinzelelo lwendalo, ukuthintela umonakalo owenziwe nge-oxidative kwiiseli zesikhumba kunye ne-DNA.

I-Collagen Activation: Ilawula imfuza ebandakanyekayo kwimveliso ye-collagen kunye ne-elastin (umzekelo, i-COL1A1, i-ELN), iqinisa i-matrix engaphandle kunye nokuphucula ukunyameka kolusu.

I-Inflammation Modulation: Inciphisa i-cytokines e-pro-ukudumba, ithambisa ulusu olucaphukisayo kunye nokuxhasa ibala elilungeleleneyo nelisempilweni.

Izibonelelo kunye nezinto eziluncedo ze-Urolithin A:

UkuSebenza okuBaselweyo kwiNzululwazi: Ixhaswa zizifundo zangaphambi kweklinikhi ezibonisa ukuphuculwa kokuqina kolusu kunye nokuncipha kweempawu zokwaluphala.

Imvelaphi yeNdalo: Ithatyathwe kwi-ellagitannins esekwe kwizityalo, enomtsalane kubathengi bobuhle obucocekileyo.

Ukuhambelana okuNgqongileyo: Isebenza ngeendlela ezahlukeneyo (iiserum, iikhrimu, iimaski) kwaye idityaniswe nezinye izinto ezisebenzayo.

Iziphumo Zexesha elide: Ikhuthaza impilo ehlala ihleli yolusu ngokujongana nokuguga kwinqanaba leeselula, hayi nje iimpawu ezingaphezulu.

Ulusu olunobuhlobo: Ayithukuthezi kwaye ilungele ulusu olubuthathaka xa isetyenziswa kwindawo ecetyiswayo

IINGCACISO ZOBUGCISA EZIPHAMBILI

IZINTO	SIMICACISO
Imbonakalo	Okumhlophe-kumhlophe ukuya kumgubo ongwevu okhanyayo
Ukuchongwa	I-HNMR iqinisekisa ubume
I-LCMS	I-LCMS Ihambelana neMW
Ubunyulu (HPLC)	≥98.0%
Amanzi	≤0.5%
Intsalela yomlilo	≤0.2%
Pb	≤0.5ppm
As	≤1.5ppm
Cd	≤0.5ppm
Hg	≤0.1ppm
E.Coli	Ibi
IMethanol	≤3000ppm
TBME	≤1000ppm
iToluene	≤890ppm
I-DMSO	≤5000ppm
I-Acetic Acid	≤5000ppm