I-Cosmate®SM, iSilymarin ibhekisa kwiqela le-flavonoid antioxidants eyenzeka ngokwendalo kwimbewu yethistle yobisi (eyayisetyenziswa ngokwembali njengeyeza lokunyanga ityhefu yamakhowa). Amacandelo eSilymarin yiSilybin, iSilibinin, iSilydianin, kunye neSilychristin. Ezi zixhobo zikhusela kwaye zinyange ulusu kuxinzelelo lwe-oxidative olubangelwa yimitha ye-ultraviolet. I-Cosmate®SM, iSilymarin nayo ineepropathi ezinamandla ze-antioxidant ezandisa ubomi beeseli. I-Cosmate®SM, iSilymarin inokuthintela umonakalo wokuvezwa kwe-UVA kunye ne-UVB. Ikwafundelwa amandla ayo okuthintela i-tyrosinase (i-enzyme ebalulekileyo ye-melanin synthesis) kunye ne-hyperpigmentation. Ekuphilisweni kwenxeba kunye nokuchasana nokuguga, i-Cosmate®SM, i-Silymarin inokuthintela ukuveliswa kwee-cytokines eziqhuba ukuvuvukala kunye ne-oxidative enzymes. Inokunyusa imveliso ye-collagen kunye ne-glycosaminoglycans (GAGs), iphakamisa uluhlu olubanzi lweenzuzo zokuthambisa. Oku kwenza ukuba ikhompawundi ibe nkulu kwiiserum ze-antioxidant okanye njengesithako esibalulekileyo kwi-sunscreens.