I-Pyrroloquinoline Quinone, i-antioxidant enamandla kunye nokhuseleko lwe-Mitochondrial kunye nokuphucula amandla

IPyrroloquinoline Quinone(PQQ)

I-Pyrroloquinoline Quinone, i-antioxidant enamandla kunye nokukhuselwa kweMitochondrial kunye nokwandisa amandla oMfanekiso

Inkcazelo emfutshane:

I-PQQ (i-Pyrroloquinoline Quinone) yi-cofactor enamandla ye-redox eyenza umsebenzi we-mitochondrial, iphucula impilo yengqondo, kwaye ikhusela iiseli kuxinzelelo lwe-oxidative - ukuxhasa amandla kwinqanaba elisisiseko.

Igama loRhwebo:Cosmate®PQQ

Igama lemveliso:Pyrroloquinoline Quinone

INCI Igama:Pyrroloquinoline Quinone

Ifomula yemolekyuli:I-C14H6N2O8

Inombolo yeCAS:72909-34-3

Imiyalezo ekwi-Intanethi I-imeyile WhatsApp

Iinkcukacha zeMveliso

Kutheni iZhonghe Fountain

Iithegi zeMveliso

Pyrroloquinoline Quinone (PQQ) yinto eyenzeka ngokwemvelo, efana ne-vitamin efumaneka emhlabeni, kwizityalo, kunye nokutya okuthile (okufana ne-kiwifruit, isipinatshi, kunye neembotyi zesoya ezibilisiweyo). Isebenza njenge-coenzyme enamandla ye-redox, idlala indima ebalulekileyo kwimveliso yamandla eselula, ukukhusela i-antioxidant, kunye neendlela zokubonisa iiseli. Ngokungafaniyo ne-antioxidants ezininzi, i-PQQ ikhuthaza ngenkuthalo ukuveliswa kwe-mitochondria entsha (mitochondrial biogenesis), ngakumbi kumalungu afuna amandla afana nengqondo nentliziyo. Isakhono sayo esikhethekileyo sokwenza amawaka emijikelo ye-redox yenza ukuba isebenze ngokugqwesileyo ekulweni uxinzelelo lwe-oxidative kunye nokuxhasa iinkqubo ezisisiseko zebhayoloji zempilo ephezulu kunye nobomi obude.

Umsebenzi ongundoqo wePQQ:
Ivuselela i-biogenesis ye-mitochondrial kunye nokwandisa amandla okuvelisa (ATP) ngaphakathi kweeseli.
Inkxaso yeMitochondrial kunye nokunyusa amandla: Ivuselela i-biogenesis ye-mitochondrial (ukwandisa inani labo), iphucula umsebenzi we-mitochondrial, kwaye iphucula ukuveliswa kwamandla eselula, inceda ukunciphisa ukukhathala.
Umsebenzi onamandla we-antioxidant: Ungathathi hlangothi ngokufanelekileyo i-radicals yamahhala, inciphisa uxinzelelo lwe-oxidative, kwaye ikhusela iiseli kumonakalo obangelwa zintlobo ze-oxygen esebenzayo.
Iziphumo ze-Neuroprotective: Ikhuthaza ukuhlanganiswa kwezinto zokukhula kwe-nerve, ixhasa ukukhula kunye nokusinda kwee-neurons, kwaye inokuphucula imisebenzi yokuqonda njengememori kunye nokugxila.
Iimpawu ezichasayo: Inqanda ukukhutshwa kwezinto eziphazamisayo, ezinceda ukunciphisa ukuvuvukala okungapheliyo okuhambelana nezifo ezahlukahlukeneyo.
Ukulawulwa kweMetabolic: Inokuphucula ubuntununtunu be-insulin, uncedo kwiswekile yegazi kunye ne-lipid balance, kunye nokuxhasa impilo yonke ye-metabolic.
Indlela yokwenza:
I-Redox Cycling: I-PQQ isebenza njengomphathi we-electron osebenza kakhulu, ephantsi kokunciphisa okuqhubekayo kunye ne-oxidation (i-20,000 + cycles), idlula kakhulu i-antioxidants eqhelekileyo njenge-Vitamin C. Oku kunciphisa i-radicals yamahhala kunye nokunciphisa uxinzelelo lwe-oxidative.
I-Mitochondrial Biogenesis: I-PQQ isebenze iindlela eziphambili zokubonisa (ngokukodwa i-PGC-1α kunye ne-CREB) ezibangela ukudalwa kwe-mitochondria entsha, enempilo kunye nokuphucula umsebenzi wezinto ezikhoyo.
I-Nrf2 Activation: Iphakamisa indlela ye-Nrf2, iphakamisa imveliso engapheliyo yomzimba ye-antioxidant enzymes enamandla (glutathione, SOD).
I-Neuroprotection: Ixhasa i-Nerve Growth Factor (NGF) synthesis kwaye ikhusela i-neurons kumonakalo we-oxidative kunye ne-excitotoxicity.
Ukubonakaliswa kweSeli: Imodareyitha umsebenzi wee-enzymes ezibandakanyekayo kwimisebenzi ebalulekileyo yeselula efana nokukhula, ukwahlukana, kunye nokusinda.Izinto eziluncedo kunye nezinto eziluncedo:
Amandla eSelula aZinzileyo: Ukwandisa ngokumangalisayo ukusebenza kakuhle kwe-mitochondrial kunye noxinaniso, okukhokelela ekwandeni kwemveliso ye-ATP kunye nokunciphisa ukukhathala.
I-Sharper Cognitive Function: Ixhasa imemori, ukugxila, ukufunda, kunye nempilo yonke yengqondo ngokukhusela i-neurons kunye nokukhuthaza i-neurogenesis.
Ukhuseleko olunamandla lwe-Antioxidant: Ibonelela ngokhuseleko olukhethekileyo, oluhlala ixesha elide kumonakalo owenziwe nge-oxidative kuwo wonke umzimba.
Inkxaso yeCardiometabolic: Ikhuthaza ukusebenza kakuhle kwentliziyo kwaye inokuxhasa imetabolism enempilo yeswekile yegazi.
Ukuhlaziywa kweSellula: Ikhuthaza ukukhula kunye nokukhuselwa kweeseli ezisempilweni ngelixa unciphisa umonakalo.
I-Synergistic Potential: Isebenza ngamandla ecaleni kwezinye izondlo zemitochondrial ezifana neCoQ10/Ubiquinol.
Iprofayili yoKhuseleko: Ibonwa njengekhuselekile (isimo se-GRAS e-US) kunye neziphumo ebezingalindelekanga ezincinci kwiidosi ezicetyiswayo.
IiNgcaciso eziPhambili zobuGcisa

Izinto	Iinkcukacha
Imbonakalo	Umgubo oBomvu oBrown
Ukuchongwa(A233/A259)UV Absorbance(A322/A259)	0.90±0.09
Ukuchongwa(A233/A259)UV Absorbance(A322/A259)	0.56±0.03
Ilahleko ekomisweni	≤9.0%
Iintsimbi ezinzima	≤10ppm
I-ARSENIC	≤2ppm
IMercury	≤0.1ppm
Inkokeli	≤1ppm
Umlinganiselo weSodium/PQQ	1.7–2.1
HPLC Ubunyulu	≥99.0%
Ubalo lweAerobic iyonke	≤1000cfu/g
Igwele kunye nenani lokungunda	≤100cfu/g

Usetyenziso.

I-Antioxidant Enamandla: I-PQQ ikhusela kakhulu ulusu kumonakalo owenziwe yimitha ye-UV, ungcoliseko, kunye noxinzelelo ngokunciphisa iiradicals zasimahla eziyingozi, ukunceda ukuthintela ukuguga kwangaphambi kwexesha.
Ukwandisa amandla oLusu kunye nokulwa nokuguga: Inceda iiseli zesikhumba zivelise amandla amaninzi (ngokuxhasa i-mitochondria), enokuphucula ukuqina, ukunciphisa imibimbi, kunye nokukhuthaza ukubonakala kolutsha.
Ikhanyisa ithoni yolusu: I-PQQ inceda ekunciphiseni amabala amnyama kunye ne-hyperpigmentation ngokuthintela ukuveliswa kwe-melanin, okukhokelela ekukhanyeni kwebala.