Kutheni iHydroxypinacolone Retinoate (HPR) yaziwa njengovulindlela ekuphuculeni umgangatho wolusu iHydroxypinacolone Retinoate (HPR) yinto ephuma phambili kwinkalo ye-retinoids ethe yatsala ingqalelo enkulu ekusebenzeni kwayo okugqwesileyo
ukuphucula umgangatho wolusu.
Njengezinye ii-retinoids ezaziwayo ezifana ne-retinoic acid esters kunye ne-retinal, i-HPR ibalasele ngokukwazi kwayo ukubonelela ngezibonelelo ezimangalisayo zesikhumba ngelixa inciphisa ukucaphuka. I-retinoids yiklasi yeekhompawundi ezivela kwi-vitamin A ekudala ithathelwa ingqalelo kakhulu kwi-dermatology ngokusebenza kwayo ekujonganeni neenkxalabo ezahlukeneyo zesikhumba ezifana ne-acne, i-pigmentation kunye neempawu zokuguga.
Phakathi kwe-retinoids, i-retinoic acid esters kunye ne-retinal ibonise iziphumo ezithembisayo. Nangona kunjalo, i-retinoids yendabuko ihlala inxulunyaniswa nokucaphuka kwesikhumba kunye nexesha elide lokuziqhelanisa, eliye labangela ukuba kukhangelwe ezinye iindlela ezilungele ulusu. Kulapho iHydroxypinacolone Retinoate (HPR) iba ngumtshintshi-mdlalo. I-HPR yi-ester ye-asidi ye-trans-trans yonke ebophelela ngokuthe ngqo kwi-retinoid receptors esikhumbeni. Esi senzo sithe ngqo siphumela kwiziphumo ezikhawulezayo nezisebenzayo kunezinye i-retinoids ezifuna ukuguqulwa ngaphakathi kwesikhumba ukuze kusebenze. Olunye uncedo oluphambili lwe-HPR kukukwazi ukuvuselela uhlaziyo lweeseli kunye ne-collagen synthesis ngelixa unciphisa iziphumo ebezingalindelekanga eziqhelekileyo ezinjengobomvu, ukugqabhuka kunye nokoma. Oku kuyenza ibe lukhetho olufanelekileyo kwabo banolusu olubuthathaka okanye abo batsha kunyango lwe-retinoid.
Ukongeza, uzinzo lwe-HPR luphawu oluphawulekayo. Ngokungafaniyo nezinye i-retinoids ezikhawuleza zithobe kwaye zilahlekelwe ukusebenza kwazo, i-HPR igcina amandla ayo, iqinisekisa iziphumo ezihambelanayo nezithembekileyo ngokuhamba kwexesha. Ke ngoko, ukufakwa kwe-HPR kwiifom zokhathalelo lwesikhumba kuphawula ukuqhubela phambili okukhulu, ukubonelela ngesisombululo esisebenzayo kodwa esithambileyo sokuphucula ukuthungwa kwesikhumba, ukunciphisa imigca emihle kunye nokukhuthaza ithoni yesikhumba. Njengoko abasebenzisi beqhubeka befuna ukhathalelo lwesikhumba olusebenzayo nolunyamezelwe kakuhle, i-hydroxypinacolone retinate inokuthi igcine indawo yayo njengesithako sobuvulindlela esiya kuguqula indlela esijongana ngayo nokhathalelo lwesikhumba. Isishwankathelo, i-innovation ye-hydroxypinacolone retinate (HPR) ilele kwisakhiwo sayo esisodwa kunye nokukwazi ukubopha ngokuthe ngqo i-receptor, ehambisa ngokufanelekileyo izibonelelo ezifunwayo zokuguga kunye nokuvuselelwa kwesikhumba. Oku kwenza i-HPR ibe nguvulindlela kuphuhliso oluqhubekayo lweemveliso ezijolise ekufezekiseni impilo, ulusu olukhangeleka luncinci.
Ixesha lokuposa: Nov-18-2024
