I-Vitamin C inefuthe lokuthintela kunye nokunyanga i-ascorbic acid, kungoko ikwabizwa ngokuba yiascorbic acidkwaye yivithamin enyibilikayo emanzini. I-vitamin C yendalo ifumaneka kakhulu kwiziqhamo ezitsha (ii-apula, ii-orenji, i-kiwifruit, njl.) kunye nemifuno (utamatisi, ukhukhamba, kunye nekhaphetshu, njl.). Ngenxa yokunqongophala kwe-enzyme ephambili kwinyathelo lokugqibela le-biosynthesis ye-vitamin C emzimbeni womntu, oko kukuthi.I-L-glucuronic acid 1,4-lactone oxidase (GLO),ivithamin C kufuneka ithathwe ekutyeni.
I-molecular formula ye-vitamin C yi-C6H8O6, eyona nto inamandla okunciphisa. Amaqela amabini e-enol hydroxyl kwi-2 kunye ne-3 ye-athomu ye-carbon kwi-molecule ahlukana ngokulula kwaye akhulule i-H +, ngaloo ndlela i-oxidizing ukwenza i-vitamin C e-dehydrogenated. ukudlala indima ebalulekileyo kumzimba womntu. Xa isetyenziswe kwintsimi yezimonyo, i-vitamin C inemisebenzi efana nokumhlophe kunye nokukhuthaza ukubunjwa kwe-collagen.
Ukusebenza kwe-vitamin C
ulusu lube mhlophe
Zimbini iindlela eziphambili ekuthi ngazoivithamin Cinefuthe elimhlophe eluswini. Indlela yokuqala kukuba ivithamin C inokunciphisa i-oxygen ebomvu ye-melanin ngexesha lenkqubo yokuvelisa i-melanin ekunciphiseni i-melanin. Umbala we-melanin unqunywe yisakhiwo se-quinone kwi-molecule ye-melanin, kwaye i-vitamin C inepropati ye-arhente yokunciphisa, enokunciphisa isakhiwo se-quinone kwisakhiwo se-phenolic. Indlela yesibini kukuba i-vitamin C inokuthatha inxaxheba kwi-metabolism ye-tyrosine emzimbeni, ngaloo ndlela inciphisa ukuguqulwa kwe-tyrosine kwi-melanin.
antioxidant
I-radicals yamahhala zizinto ezinobungozi eziveliswa yi-reactions yomzimba, eneempawu ezinamandla ze-oxidizing kwaye zingonakalisa izicubu kunye neeseli, ezikhokelela kuluhlu lwezifo ezingapheliyo.Ivithamin Ci-soluble free radical scavenger ehlanjululwa ngamanzi enokuthi isuse i-radicals yamahhala njenge-OH, R -, kunye ne-O2- emzimbeni, idlala indima ebalulekileyo kumsebenzi we-antioxidant.
Ukukhuthaza i-collagen synthesis
Kukho uncwadi olubonisa ukuba usetyenziso lwemihla ngemihla lwemixube equlathe i-5% L-ascorbic acid eluswini lunokonyusa amanqanaba embonakalo ye-mRNA yohlobo I kunye nohlobo lwe-III collagen eluswini, kunye namanqanaba embonakalo ye-mRNA yeentlobo ezintathu ze-invertase, i-carboxycollagenase. , i-aminoprocollagenase, kunye ne-lysine oxidase nazo zonyuka ngendlela efanayo, ebonisa ukuba ivithamin C inokukhuthaza ukuhlanganiswa kwe-collagen eluswini.
Impembelelo yeProoxidation
Ukongeza kwimiphumo ye-antioxidant, i-vitamin C nayo inefuthe le-prooxidant phambi kwee-ion zetsimbi, kwaye inokubangela i-lipid, i-protein oxidation, kunye nomonakalo we-DNA, ngaloo ndlela ichaphazela i-gene expression. I-Vitamin C inokunciphisa i-peroxide (H2O2) kwi-hydroxyl radical kwaye ikhuthaze ukubunjwa komonakalo we-oxidative ngokunciphisa i-Fe3 + ukuya kwi-Fe2 + kunye ne-Cu2 + kwi-Cu +. Ke ngoko, akukhuthazwa ukuba ukongeza i-vitamin C kubantu abanomxholo ophezulu wesinyithi okanye abo banezimo ze-pathological ezinxulumene nokugqithiswa kwentsimbi njenge-thalassemia okanye i-hemochromatosis.
Ixesha lokuposa: Apr-10-2023
