Masifunde skincare Isithako kunye -Ergothioneine

I-Ergothionein (ityuwa yangaphakathi ye-mercapto histidine trimethyl)

Ergothionine(EGT) sisisithinteli sendalo esikhuselayo esinokukhusela iiseli emzimbeni womntu kwaye siyinto ebalulekileyo esebenzayo emzimbeni.

Kwintsimi ye-skincare, i-ergotamine inezixhobo ezinamandla ze-antioxidant. Inokuthomalalisa ii-radicals zasimahla, inciphise umonakalo we-oxidative, ikhusele iiseli zolusu kwizinto zangaphandle zokusingqongileyo, incede ukulibazisa ukuguga kolusu, kwaye igcine ukuqina kunye nokuqaqamba kolusu.

Ukongeza kwintsimi ye-skincare, i-ergotamine nayo inezicelo kwishishini lamachiza. Umzekelo, ekuphuhliseni amanye amachiza, anokusetyenziswa njengesithako esincedisayo ukunceda ukuqinisa uzinzo kunye nokusebenza kakuhle kwechiza. Kwintsimi yokutya, kukwakho nezifundo ezivavanya ukuba nokwenzeka kokuyisebenzisa njengesongezo sokutya ukunyusa iipropathi ze-antioxidant zokutya kunye nokwandisa ubomi beshelufu.

I-Ergothionein inokhuseleko oluphezulu. Kwiimveliso ze-skincare, ukuxinwa kwezongezo ngokuqhelekileyo kuyahluka ngokuxhomekeke kwifomula kunye neemfuno ezisebenzayo zemveliso, ngokubanzi ukusuka kwi-0.1% ukuya kwi-5%.

Indima ebalulekileyo
I-Antioxidant

I-Ergothionein inokusabela ngokukhawuleza kunye ne-radicals yamahhala ukuyiguqulela kwizinto ezingenabungozi, kwaye ayilahleki lula. Kwangaxeshanye, inokugcina amanqanaba amanye ama-antioxidants (anjeVC kunye ne-glutathione), ngaloo ndlela ikhusela iiseli zesikhumba kumonakalo we-oxidative.

Indlela yokusebenza kwayo kukucoca ngokufanelekileyo - i-OH (i-hydroxyl radicals), i-chelate divalent iron ion kunye ne-ion zobhedu, ikhusela i-H2O2 ekuveliseni - OH phantsi kwesenzo se-iron okanye i-ion yobhedu, inqanda i-ion yobhedu exhomekeke kwi-oxidation ye-oksijini ene-hemoglobin, kwaye inqande. ukusabela kwe-peroxidation ekhuthaza i-arachidonic acid emva kwe-myoglobin (okanye i-hemoglobin) ixutywe H2O2.

I-Antiinflammatory
Ukuphendula okuvuthayo ngaphakathi komzimba kuyindlela eqhelekileyo yokuzikhusela kwi-stimuli, kunye nokubonakaliswa kokumelana nomzimba kwizinto eziyingozi. I-Ergothionein inokuthintela ukuveliswa kwezinto ezivuthayo, ukunciphisa izinga lokuphendula okuvuthayo, kunye nokunciphisa ukungahambi kakuhle kwesikhumba. Isebenzisa imiphumo yokuchasana nokuvuvukala ngokulawula iindlela zokubonisa i-intracellular kunye nokuthintela ukubonakaliswa kweejene ezinxulumene nokuvuvukala. Ngokomzekelo, kwisikhumba esibucayi okanye esine-acne, i-ergotamine inokunceda ukunciphisa ukuvuvukala nokukhuthaza ukulungiswa kwesikhumba.

Ukuthintela ukufota
I-Ergothionein inokuthintela ukuqhekeka kwe-DNA okubangelwa kukukhanya kwe-ultraviolet kunye ne-hydrogen peroxide, kwaye inokukhupha iiradicals zasimahla kwaye ifunxe imitha ye-ultraviolet ukuphelisa umonakalo kwi-DNA. Kuluhlu lokufunxa kwi-ultraviolet, i-ergothionein inobude obufanayo nobo be-DNA. Ke ngoko, i-ergothionein inokusebenza njengesihluzo somzimba kwimitha ye-ultraviolet.

Okwangoku, uphando oluninzi lubonise ukuba i-ergotamine sisithako esisebenzayo se-sunscreen esinokuthi sithintele umonakalo wolusu kwimitha ye-UV.
Ukukhuthaza ukuveliswa kweprotheni ye-collagen
I-Ergothionein inokukhuthaza ukwanda kwenani le-fibroblasts kwaye ivuselele ukuhlanganiswa kwe-collagen kunye ne-elastin. Ikhuthaza ukubonakaliswa kofuzo lwe-collagen kunye ne-protein synthesis ngokuvula iimolekyuli ezithile zomqondiso ngaphakathi kweeseli.