I-Cosmate®HPR10, ekwabizwa ngokuba yi-Hydroxypinacolone Retinoate 10%,HPR10, enegama le-INCI i-Hydroxypinacolone Retinoate kunye ne-Dimethyl Isosorbide, yenziwe yi-Hydroxypinacolone Retinoate kunye ne-Dimethyl Isosorbide, yi-ester ye-all-trans Retinoic Acid yendalo kunye ne-synthetic acid, yevithamini A, ekwazi ukubophelela kwi-retinoid receptors. Ukubophelela kwe-retinoid receptors kunokuphucula ukubonakaliswa kofuzo, okuguqula ngokufanelekileyo imisebenzi ephambili yeselula.