Ergothioneine

I-Cosmate^®EGT,Ergothioneine(EGT) yinto ebalulekileyo esebenzayo kwi-boday yabantu.I-Ergothioneine ifunyenwe ngokuvundiswa okuninzi kwe-Hericium Erinaceum & Tricholoma Matsutake.Ukuvutshelwa okuninzi kunokunyusa isivuno seL-Ergothioneine, okuyi-sulfure equkethe i-amino acid histidine, i-antioxidant ekhethekileyo ezinzileyo kunye ne-cytoprotective agent, ekhoyo emzimbeni womntu.I-Ergothioneine inokudluliselwa ngaphakathi kwe-mitochondria ngu-transporter OCTN-1 kwi-keratinocytes yesikhumba kunye ne-fibroblasts, ngaloo ndlela idlala i-anti-oxid

I-Cosmate^®I-EGT yi-antioxidant enamandla kwaye ibonakalise ukuba ikhusela ulusu ekonakalisweni lilanga kunye nezinye iimpawu zokuguga. I-Cosmate^®I-EGT ikhusela iiseli kumonakalo owenziwe yimitha ye-ultraviolet. Inciphisa iintlobo zeoksijini esebenzayo emzimbeni kwaye inokunceda ukulungisa i-DNA eyonakaliswe yimitha ye-ultraviolet. Kwakhona inqanda impendulo ye-apoptotic yeeseli ezivezwe kwimitha ye-UVA, ukwandisa ukusebenza kwazo.I-Ergothioneine inefuthe elinamandla le-cytoprotective. I-Cosmate^®EGT anti-ukudumba kunye ne-antioxidant iipropathi ezisetyenziswa kwizithambiso zelanga. I-UVA elangeni inokungena kwidermis yolusu kwaye ichaphazele ukukhula kweeseli ze-epidermal, zenze iiseli zolusu ziguge kwangaphambili, kwaye i-UVB kulula ukukhokelela kumhlaza wolusu. I-Ergothione yafunyanwa ukunciphisa ukubunjwa kweentlobo ze-oksijini esebenzayo kunye nokukhusela iiseli kumonakalo wemitha. Ikwavuselela imveliso ye-collagen eluswini kwaye inciphisa ukudumba. Njengelinye lamalungu okugqibela ukufumana izondlo, kubalulekile ukuba unikeze ngezi zondlo kwiimveliso zokhathalelo lwesikhumba. Ekugxineni kwe-physiological, i-ergothioneine ibonisa i-diffusional inactivation enamandla ye-hydroxyl radicals kwaye ikhusela ukuveliswa kwe-oksijini ye-athomu, ekhusela i-erythrocytes kwi-neutrophils ekusebenzeni ngokuqhelekileyo okanye kwiindawo ezivuthayo ezivuthayo. Xa idityaniswe namanye ama-antioxidants kunye neemveliso zokunakekelwa kwesikhumba, i-ergothioneine iyasebenza ekunciphiseni iimpawu zokuguga kunye nokuphucula ukubonakala ngokubanzi kwesikhumba.

Ergothioneine Imisebenzi ephambili

* Ukhuseleko lwe-Antioxidant: I-Ergothioneine sisixhobo esinamandla sokulwa ne-antioxidant esinokutshabalalisa ngokufanelekileyo ii-radicals zasimahla ezenziwe yimiba yokusingqongileyo njengemitha ye-UV kunye nongcoliseko. Ngokwenza njalo, i-Ergothioneine inceda ukukhusela umonakalo we-oxidative kwiiseli zesikhumba, inciphisa ukuthotywa kwe-collagen kunye ne-elastin fibers, kwaye ngaloo ndlela ilibazise ukubonakala kwemibimbi kunye nemigca emihle, igcina ulusu lubukeka lulutsha kwaye luqinile.
*Iimpembelelo ezichasene nokudumba:I-Ergothioneine inamandla okuchasa ukudumba. I-Ergothioneine inokunciphisa ukubomvu kwesikhumba, ukudumba, kunye nokucaphuka okubangelwa zizinto ezahlukeneyo ezifana ne-acne, i-allergies, kunye ne-dermatitis yoqhagamshelwano. I-Ergothioneine ithambisa ulusu kwaye inceda ekunciphiseni ukurhawuzelelwa kunye nokungonwabi, iyenze ibe luncedo ngakumbi kwiintlobo zolusu ezibuthathaka kunye nezisebenzayo.
* Ukunyibilika kolusu kunye nomsebenzi woMqobo: I-Ergothioneine inokuphucula amandla okugcina ukufuma kwendalo ngokuphucula umsebenzi womqobo wolusu. Inceda ukutshixa kubumanzi, yenze ulusu luzive lunamanzi ngakumbi, lugudile, kwaye luthambile. Oku komeleza ukuxhathisa ulusu kwizinto eziyingozi zangaphandle kunye noxinzelelo lokusingqongileyo.                                         

* Ukugcinwa kweMpilo yeNwele: Kwiimveliso zokunakekelwa kweenwele, i-Ergothioneine idlala indima ekukhuseleni iifollicle zeenwele emonakalweni we-oxidative. Inceda ukuthintela ukuqhekeka kweenwele, ukuphucula ukuqina kweenwele kunye nokuqaqamba, kunye nokukhuthaza ukukhula kweenwele okunempilo. I-Ergothioneine iyasebenza ngokukodwa ekunyangeni iinwele ezonakalisiweyo ezibangelwa kukuhombisa ubushushu, unyango lweekhemikhali, kunye nongcoliseko lokusingqongileyo.

I-Ergothioneine Mechanism of Action

*UkuHlwa kweRadical yasimahla: Ulwakhiwo olukhethekileyo lwemolekyuli ye-Ergothioneine iyenza ikwazi ukusabela ngokuthe ngqo ngeeradicals zasimahla, ukunikela ngee-elektroni ukuze zithobe kwaye ziphelise ukusabela komonakalo we-oxidative. Iqela layo le-thiol libaluleke kakhulu kule nkqubo, njengoko ikwazi ukusebenzisana ngokukhawuleza kunye neentlobo ze-oksijini ezisebenzayo kunye nezinye ii-radicals zamahhala.
* Ukumodareyithwa kweeNdlela zokuSayina ezivuthayo: I-Ergothioneine inokuphazamisa ukusebenza kweendlela ezithile zokubonakalisa ukuvuvukala kwiiseli. Ivimbela ukuveliswa kunye nokukhululwa kwe-cytokines e-pro-inflammatory kunye nabalamli, njenge-TNF-α, i-IL-6, kunye ne-COX-2, ngaloo ndlela inciphisa impendulo yokuvuvukala kwinqanaba leselula.
*I-Metal Chelation: I-Ergothioneine inamandla okuhlaziya i-ion zetsimbi, ngakumbi ubhedu kunye nentsimbi. Ngokuzibophelela kwezi ion zetsimbi, zibathintela ekuthatheni inxaxheba kwi-Fenton reactions kunye nezinye iinkqubo ze-redox ezinokuthi zivelise i-radicals enobungozi yamahhala, ngaloo ndlela inciphisa uxinzelelo lwe-oxidative.
* Ukomelezwa kweNkqubo yoKhuseleko lweSellula: I-Ergothioneine inokulawula ukubonakaliswa kwe-antioxidant enzymes kunye neeprotheni kwiiseli, ezifana ne-glutathione peroxidase kunye ne-superoxide dismutase. Oku kunceda ukomeleza inkqubo yokhuselo yeseli ye-antioxidant kunye nokuphucula amandla ayo okuxhathisa umonakalo owenziwe nge-oxidative.

Ergothioneine izinto eziluncedo

*Uzinzo oluphezulu: I-Ergothioneine izinzile phantsi koluhlu olubanzi lweemeko, kubandakanywa amaxabiso ahlukeneyo e-pH kunye namaqondo obushushu. Olu uzinzo luvumela ukuba lugcine umsebenzi walo webhayoloji kunye nokusebenza kakuhle kwiindlela ezahlukeneyo zokuzihombisa kunye nokunyamekela komntu, nokuba zi-aqueous, i-oil-based, okanye i-emulsion systems.
* I-Biocompatibility egqwesileyo: I-Ergothioneine inyamezeleke kakuhle ulusu kwaye inobuthi obuncinci kunye nokucaphukisa amandla.I-Ergothioneine ifanelekile ukusetyenziswa kwiimveliso kuzo zonke iintlobo zesikhumba, kubandakanywa ulusu olubucayi, ngaphandle kokubangela ukusabela okungathandekiyo njengokungabikho komzimba okanye ukucaphuka kwesikhumba.
* Ukuhambelana okuNgqongileyo: I-Ergothioneine inokudibaniswa ngokulula kunye nezinye izithako ezisebenzayo eziqhelekileyo ezisetyenziselwa izimonyo kunye neemveliso zokunyamekela, ezifana neevithamini, izicatshulwa zezityalo, kunye ne-hyaluronic acid. Ibonisa i-synergy elungileyo kunye nezi zithako, ukunyusa ukusebenza kakuhle ngokubanzi kokuqulunqwa.
*Umthombo oZinzileyo: I-Ergothioneine inokuveliswa ngeenkqubo zokuvundisa ezizinzileyo kusetyenziswa ii-microorganisms. Oku kubonelela ngomthombo ohambelana nokusingqongileyo kunye nokuhlaziywa ngokutsha kwesithako, ukuhlangabezana nemfuno ekhulayo yeemveliso ezizinzileyo kunye ne-eco-friendly kushishino lobuhle.

Yiyiphi imveliso equlethe i-Ergothioneine

I-Skincare ProductsAnti-aging Creams kunye neeSerums: I-Ergothioneine isoloko idityaniswe kwiindlela zokulwa nokuguga ukulwa nemibimbi, ukuphucula ukuqina kwesikhumba, kunye nokuphucula ukuqina kwesikhumba. Isebenza kwi-synergy kunye nezinye izithako ezichasene nokuguga ukubonelela ngeziphumo ezibanzi zokuchasa ukuguga.
* Izikhuseli zelanga: Ngenxa yeepropathi zayo zokulwa ne-antioxidant, i-Ergothioneine inokongezwa kwizikrini zelanga ukunyusa ukhuseleko lwazo kumonakalo owenziwe yi-UV-oxidative. I-Ergothioneine inceda ukuthintela ukutshiswa lilanga, umonakalo weDNA, kunye nokuguga kwangaphambi kwexesha okubangelwa kukugqatswa lilanga.
*Izinto zokuthambisa kunye neeMaski zobuso: Kwizinto zokuthambisa kunye neemaski zobuso, i-Ergothioneine inceda ekuphuculeni ukumanzisa kolusu kunye nokugcina amanqanaba okufuma kolusu. Yenza ulusu luzive luthambile kwaye luthambile, kwaye lunokunceda ekunciphiseni ukubonakala kwemigca ecolekileyo ebangelwa kukoma.
* Unyango lwe-Acne kunye ne-Blemish: I-anti-inflammatory kunye ne-antioxidant ye-Ergothioneine yenza ukuba ilungele ukusetyenziswa kwi-acne kunye nonyango lwebala. Inokunceda ukunciphisa ukuvuvukala, ukuthintela ukukhula kwebhaktheriya, kunye nokukhuthaza ukuphiliswa kwezilonda ze-acne.
Iimveliso zeNwele IiShampoos kunye ne-Conditioners: I-Ergothioneine inokufumaneka kwii-shampoos kunye ne-conditioners ukuphucula impilo yeenwele. Inceda ukulungisa iinwele ezonakalisiweyo, ukunciphisa i-frizz, kunye nokwandisa ukuqaqamba kweenwele kunye nokulawula.
*IiMaski zeNwele kunye noNyango: Kwiimaski zeenwele kunye nonyango lwemeko enzulu, i-Ergothioneine ibonelela ngesondlo esinamandla kunye nokhuseleko kwiinwele. Ingena kwi-shaft yeenwele ukomeleza iinwele ngaphakathi kwaye iphucule umgangatho wayo wonke.
*IiSerum ze-scalp: Kukhathalelo lwe-scalp, iiserum ezine-Ergothioneine zinokunceda ukuthomalalisa i-scalp, ukunciphisa inkwethu kunye nokurhawuzelelwa, kunye nokukhuthaza indawo esempilweni ye-scalp yokukhula kakuhle kweenwele.
*Iimveliso zoNyango loMzimba kunye neeCreams: I-Ergothioneine inokongezwa kwi-lotion yomzimba kunye ne-creams ukuthambisa nokukhusela ulusu. Inceda ekuphuculeni ukumila kolusu, iyenze ibemtyibilizi kwaye ibengezele.
*IiSanitizer zezandla kunye neesepha: Kwizicoci zezandla kunye neesepha, i-Ergothioneine inokubonelela ngezibonelelo ze-antioxidant kunye ne-anti-ukudumba, inceda ukunqanda ukoma kolusu kunye nokucaphuka okubangelwa kukuhlamba izandla rhoqo.

• Iiparamitha zobuGcisa:

Usetyenziso:

*Ukuchasa ukuguga

*Antioxidation

*Isikrini seLanga

*Ukulungiswa kolusu

*Ubonelelo oluthe ngqo kuMzi-mveliso

*Uxhaso lobuchwepheshe

*Inkxaso yeesampuli

*Inkxaso yoMyalelo weTyala

*Inkxaso yoMyalelo omncinci

*Utshintsho oluqhubekayo

*Gcoba kwizithako ezisebenzayo

*Zonke izithako ziyalandeleka