Azelaic acid

Azelaic acidisetyenziswa ikakhulu kunyango lwasekhaya lwe-acne ephakathi ukuya ephakathi kwaye inokudibaniswa ne-antibiotics yomlomo okanye unyango lwehomoni. Isebenza kuzo zombini i-acne vulgaris kunye ne-acne vulgaris evuthayo.
Iasidi yeAzeoic ingasetyenziselwa ukunyanga ulusu lwebala, kubandakanya i-melasma kunye ne-post inflammatory pigmentation, ngakumbi kubantu abanolusu olumnyama. Kucetyiswa ukuba endaweni ye-hydroquinone. Njenge-tyrosinase inhibitor, i-azelaic acid inokunciphisa ukuhlanganiswa kwe-melanin.

Umsebenzi kunye noMsebenzi:
1) Ukunciphisa ukuvuvukala. I-asidi ye-Adipic inokuchasana okanye inciphise i-radicals yamahhala ebangela ukuvuvukala. Inefuthe elibonakalayo lokuzola eluswini kwaye inceda ukuphucula ububomvu kunye nokudumba.
2) Ithoni yesikhumba esifanayo. Inokunciphisa umbala kwaye inqanda i-enzyme ebizwa ngokuba yi-tyrosinase, enokubangela ukuba kubekho umbala ogqithisileyo okanye amabala amnyama esikhumbeni. Kungenxa yoko le nto i-azelaic acid isebenza kakhulu kwi-acne, i-post scars kunye ne-melasma.
3) Ukulwa ne-acne. I-Azeoic acid inokubulala ibhaktheriya eluswini olubangela i-acne. Inokunciphisa umsebenzi wePropionibacterium, ibhaktheriya efumaneka kwi-acne, kuba ine-antibacterial (ukunciphisa ukuveliswa kwebhaktheriya) kunye ne-bactericidal (iibhaktheriya ezibulalayo),
4) Umphumo wobumnene, unceda ukukhupha ama-pores kunye nokuphucula umgangatho wolusu
I-5) Izinto ezibalulekileyo zokuzola kwesikhumba zinokunciphisa uvakalelo kunye nezibonda
6) Impembelelo ye-Antioxidant, eyenza ulusu lube nempilo

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